Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp471 | Other diseases of bone and mineral metabolism | ECTS2013

Long-term energy deficiency in mice induces bone alterations reversed by long-term recovery

Zgheib Sara , Lucas Stephanie , Mequinion Mathieu , Broux Odile , Leterme Damien , Hardouin Pierre , Viltart Odile , Chauveau Christophe

Anorexia nervosa (AN) a condition of profound undernutrition, is characterized by alterations in neuroendocrine and metabolic functions. Among the serious pathological consequences of this eating disorder, osteoporosis is often observed and persists after recovery, leading to a high fracture risk.To study particularly bone alterations and recovery, a long term mouse model has been developed. In this model named separation-based anorexia (SBA) – a ch...